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Recombinant Human IL-21 Protion

Cat NoBIOS-2016A
Conjugate
Type重组蛋白
SourceHuman
Size20 ug; 100ug; 1 mg
ApplicationImmunology
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in 0.01 M PBS; pH 7.4.
StorageStore at -20 degree for long term.
SynonymsCVID11;IL-21;Interleukin 21;白细胞介素21
Purification> 95% by SDS-PAGE
MolecularWeight15.6 kDa
DescriptionHuman IL21 isoform 1 (Q9HBE4-1) (Gln30-Ser162) in Escherichia coli.
BackgroundIL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as a therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).
We can provide a variety of products such as diagnostic proteins; target proteins; cytokines; etc.
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