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Cat No | BQSB-1235 |
Conjugate | |
Type | 重组兔单抗 |
Clone | BT3179 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IHC-P; IHC-F; ICC/IF; IF; IP; Flow-Cyt |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 半胱胺酸蛋白酶蛋白14;Integrin alpha-5;VLA-5;CD49e;ITGA5;FNRA |
Purification | |
MolecularWeight | |
Description | |
Background | Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. |