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Recombinant Rabbit Anti-RING2 Monoclonal Antibody, clone BT3640

Cat NoBQSB-1696
Conjugate
Type重组兔单抗
CloneBT3640
SourceRabbit
TagN/A
Size1 mg
ApplicationWB; IHC-P; IHC-F; ICC/IF; IF; Flow-Cyt
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
StorageShipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Synonyms环指蛋白2;BAP1;DING;BAP-1;HIPI3;RING2;RING1B
Purification
MolecularWeight
Description
BackgroundActs as the main E3 ubiquitin ligase on histone H2A of the PRC1 complex, while RING1 may rather act as a modulator of RNF2/RING2 activity (Probable). Association with the chromosomal DNA is cell-cycle dependent. In resting B- and T-lymphocytes, interaction with AURKB leads to block its activity, thereby maintaining transcription in resting lymphocytes.Also acts as a negative regulator of autophagy by mediating ubiquitination of AMBRA1, leading to its subsequent degradation.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.
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