Recombinant Rabbit Anti-TRIM29 Monoclonal Antibody, clone BT4004
Cat No | BQSB-2060 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT4004 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 共濟(jì)失調(diào)毛細(xì)血管擴(kuò)張癥D相關(guān)蛋白;ATDC;TRIM29 |
Purification | |
MolecularWeight | |
Description | |
Background | Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.