Recombinant Rabbit Anti-CD19 Monoclonal Antibody, clone BT2633
Cat No | BQSB-685 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT2633 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB,IHC-P,IF,IHC-F |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | LRP2_HUMAN;Low-density lipoprotein receptor-related protein 2;LDL receptor related protein 2;DBS;GP330;LRP-2;Glycoprotein 330 (gp330);Megalin |
Purification | |
MolecularWeight | |
Description | |
Background | This gene encodes a member of the immunoglobulin gene superfamily. Expression of this cell surface protein is restricted to B cell lymphocytes. This protein is a reliable marker for pre-B cells but its expression diminishes during terminal B cell differentiation in antibody secreting plasma cells. The protein has two N-terminal extracellular Ig-like domains separated by a non-Ig-like domain, a hydrophobic transmembrane domain, and a large C-terminal cytoplasmic domain. This protein forms a complex with several membrane proteins including complement receptor type 2 (CD21) and tetraspanin (CD81) and this complex reduces the threshold for antigen-initiated B cell activation. Activation of this B-cell antigen receptor complex activates the phosphatidylinositol 3-kinase signalling pathway and the subsequent release of intracellular stores of calcium ions. This protein is a target of chimeric antigen receptor (CAR) T-cells used in the treatment of lymphoblastic leukemia. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.