Recombinant Rabbit Anti-HIF Prolyl Hydroxylases Monoclonal Antibody, clone BT4389
Cat No | BQSB-2445 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT4389 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IHC-P; IHC-F; IP; Flow-Cyt; IF |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 缺氧誘導(dǎo)因子脯氨酰羥化酶4;EGLN4;HIFPH4;Hypoxia inducible factor prolyl 4 hydroxylase;P4H with transmembrane domain;P4htm;PH4;PHD4;Proline 4 hydroxylase;Prolyl hydroxlase domain containing 4 |
Purification | |
MolecularWeight | |
Description | |
Background | Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.