Recombinant Rabbit Anti-MEK5 Monoclonal Antibody, clone BT4846
Cat No | BQSB-2902 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT4846 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; ICC/IF |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 絲裂原活化蛋白激酶激酶5;MAP2K5;HsT17454;MAPKK 5;MEK 5;MAPKK5;MEK5;MKK5;MAP kinase kinase 5;PRKMK5;MAP kinase kinase MEK5b;MAPK/ERK kinase 5 |
Purification | |
MolecularWeight | |
Description | |
Background | Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. As part of the MAPK/ERK signaling pathway, acts as a negative regulator of apoptosis in cardiomyocytes via promotion of STUB1/CHIP-mediated ubiquitination and degradation of ICER-type isoforms of CREM. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.