Recombinant Rabbit Anti-SET Monoclonal Antibody, clone BT2353
Cat No | BQSB-401 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT2353 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IHC-P; IHC-F; ICC/IF; IF |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | SET易位蛋白/髓系白血病相關(guān)蛋白;L type amino acid transporter 3;L-type amino acid transporter 3;Large neutral amino acids transporter small subunit 3;LAT3_HUMAN;PB39;POV1;Prostate cancer overexpressed gene 1 protein;R00504;SLC43A1 |
Purification | |
MolecularWeight | |
Description | |
Background | Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMAactivated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.