Recombinant Rabbit Anti-TOP2A Monoclonal Antibody, clone BT2942
Cat No | BQSB-998 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT2942 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IHC-P; IHC-F; IF |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | DNA拓普西異構(gòu)酶Ⅱ;muscle Actin;ACTS_HUMAN;Actin;alpha skeletal muscle;Alpha-actin-1;ACTA1;ACTA;ASMA;CFTD;CFTD1;CFTDM;MPFD;NEM1;NEM2;NEM3;Actin alpha skeletal muscle;actin;alpha 1;skeletal muscle 1;actin;alpha 1;skeletal muscle;actina;aktin;alpha Actin 1;alpha skeletal muscle Actin;alpha skeletal muscle;alpha-actin;Beta cytoskeletal actin;nemaline myopathy type 3 |
Purification | |
MolecularWeight | |
Description | |
Background | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.